In the pharmaceutical industry micro-encapsulation is often used for drug delivery. By means of controlled and sustained release of the Active Pharmaceutical Ingredient (API), a better therapeutic effect, less side effects and higher patient convenience / compliance is achieved. Other applications are delivery of poorly soluble APIs, taste masking, targeted delivery, improving stability.
Droplet production with the use of microchannels, otherwise called microfluidic emulsification, is a much-reported method to make uniform and controlled soft matter structures, like emulsions, microcapsules, and microspheres.
Microfluidics is the controlled process of droplet formation out of two or more liquids. The process takes place in channels of only a few microns wide. Once droplets are formed they can be solidified in the channel by extracting the solvent or adding a third liquid, such as a cross-linker.
Microfluidics is widely recognized as the most controlled method for micro-encapsulation. EmulTech's successful scalability and cGMP work ensure microfluidics has a viable path to market.
EmulTech's process is based on the patented model for encapsulation in microfluidic channels. The model translates material specific parameters and desired outcomes to process conditions. The model greatly reduces process related uncertainty and allows for quick development of the desired particle. This approach ensures high batch-to-batch consistency and reproducibility during scale up.
The heart of the INFINITY platform is EmulTech's unique model. The model ensures easy operation and helps you quickly identify the right proces conditions to obtain the desired results. Furthermore the model warrants high batch-to-batch consistancy and easy translation from the INFINITY Mini to the INFINITY Lab and scale up to clinical and market relevant volumes.