Controlled release


Microencapsulation of a drug in a biodegradable polymer matrix leads to a controlled release of the drug over a period of time through slow degradation of the polymer matrix after injection. This sustained release leads to a constant blood level of the drug, which improves the therapeutic effect and reduces side-effects.

Additionally, the switch from daily to monthly administration leads to higher patient convenience and compliance. This is especially beneficial for chronic conditions. The formulation of controlled release systems is a multifactorial complex process. High control of particle characteristics during production is crucial and can be achieved with Emultech’s microfluidic emulsification.

Advantages for controlled release

  • Controlled drug release through control over particle size
  • High drug loading through high encapsulation efficiencies
  • Improved injectability through uniformity of particles
  • Encapsulation of proteins due to benign nature of the process
  • No waste of expensive raw materials since no sieving is required

Sustained release

Microsphere size and uniformity influence the duration and uniformity of drug release.

Application areas for controlled release

  • Oncology

  • Antipsychotics

  • Osteoathritis

  • HIV

  • Infectious diseases

  • Blood thinners

Learn more about other applications

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